Mixing Tank Design Calculations

Mixing tank calculations are an important part of chemical engineering

Simulations and calculations used in combination with hydrodynamic parameters can lead to efficient product processing and decrease the development time. This whole process will result in the optimized production of industrial chemical products (Alshanski et al., 2018). The equipment and calculations used are highly required to expand the yield or scale-up on a large scale. The combination of equipment (Bentolila, 2006) and calculation drastically decreases the experimental work required to solve issues of scale-up or to improve a process that runs regularly on a large scale.

After recognizing the whole process, whether it is chemical, biological, or physical, production can be developed on large scale via a combination of hydrodynamic data together with chemical processes phenomena.

In the same manner, glass reactors are used for the processing of materials in the chemical industry such as pharmaceuticals, API, food, fine chemicals, biotechnology, and others. These reactors can also be used to obtain kinetic constants and mixing effects (Akiti, Yeboah, Bai, & Armenante, 2005).

VisiMix software is commonly used to aid in chemical mixing simulation and chemical process calculations. This software is used by numerous chemical plants to solve chemical engineering problems (Bentolila, Alshanski, Novoa, & Gilon, 2018).

VisiMix assists in recognizing the link between mixing parameters and experimental work, and in providing “know-how” about the process. This software is extremely advantageous in scale-up activities and eliminates “outside of specifications” material. This occurs when different material sizes are used during the procedure. The main function of VisiMix software in this process is to calculate the recognized hydrodynamics parameters in order to optimize the process (Bentolila et al., 2018).



Akiti, O., Yeboah, A., Bai, G., & Armenante, P. (2005). Hydrodynamic effects on mixing and competitive reactions in laboratory reactors. Chemical Engineering Science, 60, 2341-2354. doi:10.1016/j.ces.2004.10.049

Alshanski, I., Bentolila, M., Gitlin-Domagalska, A., Zamir, D., Zorsky, S., Joubran, S., . . . Gilon, C. (2018). Enhancing the Efficiency of the Solid Phase Peptide Synthesis (SPPS) Process by High Shear Mixing. Organic Process Research & Development, 22(9), 1318-1322.

Bentolila M. (2006). Predicting mixing in stirred reactor and micro reactor. Research Proposal for PhD. in Chemical Engineering. Israel Institute of Technology.

Bentolila, M., Alshanski, I., Novoa, R., & Gilon, C. (2018). Optimization of Chemical Processes by the Hydrodynamic Simulation Method (HSM). ChemEngineering, 2(2), 21.

VisiMix Video

The Influence of Mixing in the Process
New methodology using VisiMix software for the purpose of checking the influence of mixing in the processes.

VisiMix Demo Operation
Learning how to input data into the VisiMix software and get results the will help us understand the influence of mixing in our processes.

Lab Experiments
Learning how to set up the relevant experiments at the lab scale, to develop the processes from an engineering point of view.